episcanpy.api.tl.louvain

episcanpy.api.tl.louvain(adata, resolution=None, random_state=0, restrict_to=None, key_added='louvain', adjacency=None, flavor='vtraag', directed=True, use_weights=False, partition_type=None, partition_kwargs=mappingproxy({}), neighbors_key=None, obsp=None, copy=False)

Cluster cells into subgroups [Blondel08] [Levine15] [Traag17].

Cluster cells using the Louvain algorithm [Blondel08] in the implementation of [Traag17]. The Louvain algorithm has been proposed for single-cell analysis by [Levine15].

This requires having ran neighbors() or bbknn() first, or explicitly passing a adjacency matrix.

Parameters

adata : AnnDataAnnData

The annotated data matrix.

resolution : float | NoneOptional[float] (default: None)

For the default flavor ('vtraag'), you can provide a resolution (higher resolution means finding more and smaller clusters), which defaults to 1.0. See “Time as a resolution parameter” in [Lambiotte09].

random_state : None | int | RandomStateUnion[None, int, RandomState] (default: 0)

Change the initialization of the optimization.

restrict_to : Tuple[str, Sequence[str]] | NoneOptional[Tuple[str, Sequence[str]]] (default: None)

Restrict the clustering to the categories within the key for sample annotation, tuple needs to contain (obs_key, list_of_categories).

key_added : strstr (default: 'louvain')

Key under which to add the cluster labels. (default: 'louvain')

adjacency : spmatrix | NoneOptional[spmatrix] (default: None)

Sparse adjacency matrix of the graph, defaults to neighbors connectivities.

flavor : {‘vtraag’, ‘igraph’, ‘rapids’}Literal[‘vtraag’, ‘igraph’, ‘rapids’] (default: 'vtraag')

Choose between to packages for computing the clustering. 'vtraag' is much more powerful, and the default.

directed : boolbool (default: True)

Interpret the adjacency matrix as directed graph?

use_weights : boolbool (default: False)

Use weights from knn graph.

partition_type : Type[MutableVertexPartition] | NoneOptional[Type[MutableVertexPartition]] (default: None)

Type of partition to use. Only a valid argument if flavor is 'vtraag'.

partition_kwargs : MappingMapping[str, Any] (default: mappingproxy({}))

Key word arguments to pass to partitioning, if vtraag method is being used.

neighbors_key : str | NoneOptional[str] (default: None)

Use neighbors connectivities as adjacency. If not specified, louvain looks .obsp[‘connectivities’] for connectivities (default storage place for pp.neighbors). If specified, louvain looks .obsp[.uns[neighbors_key][‘connectivities_key’]] for connectivities.

obsp : str | NoneOptional[str] (default: None)

Use .obsp[obsp] as adjacency. You can’t specify both obsp and neighbors_key at the same time.

copy : boolbool (default: False)

Copy adata or modify it inplace.

Return type

AnnData | NoneOptional[AnnData]

Returns

None

By default (copy=False), updates adata with the following fields:

adata.obs['louvain'] (pandas.Series, dtype category)

Array of dim (number of samples) that stores the subgroup id ('0', '1', …) for each cell.

AnnData

When copy=True is set, a copy of adata with those fields is returned.